2024

  1. Singh M, Debas A, Joshi G, Okajima MK, Rajan R, Matsumura K, Kaneko T*. Enhancing Gelatine Hydrogel Robustness with Sacran-Aldehyde: A Natural Cross-Linker Approach. Polysaccharides, 5, 320-331 (2024)
  2. Hayashi M, Takahashi R, Vu TN, Matsumura K, Yamago S, Yusa SI*. Thermoresponsive behavior of dual hydrophilic diblock copolymers prepared via organotellurium-mediated living radical polymerization. Polymer Journal, 56, 1129–1141 (2024)
  3. Supachettapun C, Asif Ali M, Muangsin N, Takada K, Matsumura K, Okajima MK, Kaneko T*. Cyanobacterial Ampholyte Hydrogels Developed by the Cationization of Sulfated Polysaccharides and Their Cell-Compatibility. Biomacromolecules, 25, 5995-6006 (2024)
  4. Rajan R*, Furuta T, Zhao D, Matsumura K*. Molecular mechanism of protein aggregation inhibition with sulfobetaine polymers and their hydrophobic derivatives. Cell Rep. Phys. Sci., 5, 102012 (2024)
  5. Nakada M*, Kanda J, Uchiyama H, Matsumura K. Nanoscale Intracellular Ultrastructures Affected by Osmotic Pressure Using Small-Angle X-ray Scattering. Biophys. Chem., 312, 107287 (2024)
  6. Hirose T, Rajan R, Miyako E*, Matsumura K*. Liquid metal-polymer nano-microconjugations as an injectable and photo-activatable drug carrier. Mol. Sys. Des. Eng. 9, 781-789 (2024)
  7. Rajan R*, Matsumura K*. Design of Polysulfobetaine Derivatives for Enhanced Inhibition of Protein Aggregation. Polym. Chem. 15, 2040-2046 (2024)
  8. Kumar N, Singh P, Zhao D, Rajan R*, Matsumura K*. Novel Approach to Enhancing the Anticancer Efficacy of Methyl Jasmonate with PEG-incorporated Cationic Polymers. Mater. Adv., 5, 5586-5594 (2024)
  9. Kumar N, Nakaji-Hirabayashi T, Kato M, Matsumura K*, Rajan R*. Design of Highly Selective Zn-Coordinated Polyampholyte for Cancer Treatment and Inhibition of Tumor Metastasis. Biomacromolecules, 25, 1481-1490 (2024)

2024 ORIGINAL PAPERS

2023

  1. Seki S, Kawabe T, Yamazaki W, Matsumura K, Oikawa T, Obata T, Higashiya M, Yano M, Eto T, Cryopreservation of rat embryos at all developmental stages by small-volume vitrification procedure and rapid warming in cryotubes. Sci Rep, 13, 20903 (2023)
  2. Yamasaki R, Rajan R, Matsumura K*, Enhancement of cryopreservation with intracellularly permeable zwitterionic polymers. Chem. Comm. 59, 14001-14004 (2023)
  3. Taoka Y, Saari RA, Kida T, Yamaguchi M. Matsumura K*. Enhancing the mechanical properties of Poly (vinyl alcohol) fibers by lithium iodide addition. ACS Omega, 8, 32623-32634 (2023)
  4. Maemura D, TS Le, Takahashi M, Matsumura K, Maenosono S. Optogenetic CalciumIon Influx in Myoblasts and Myotubes by Near-Infrared Light Using Upconversion Nanoparticles. ACS Appl. Mater. Interfaces, 15, 42196-42208 (2023)
  5. Dai X, Zhao D, Matsumura K*, Rajan R*. Polyampholytes and Their Hydrophobic Derivatives as Excipients for Suppressing Protein Aggregation. ACS Appl. Bio Mater., 6, 2738-2746 (2023)
  6. Jin H, Choi W, Matsumura K, Hyon SH, Gen Y, Hayashi M, Kawabata T, Ijiri M, Miyoshi K. Improved fertility of frozen‐thawed porcine spermatozoa with 3, 3‐dimethylglutaric anhydride poly‐L‐lysine as a novel cryoprotectant. Animal Sci. J., 94, e13821 (2023)
  7. Rajan R*, Kumar N, Zhao D, Dai X, Kawamoto K, Matsumura K*, Polyampholyte‐Based Polymer Hydrogels for the Long‐Term Storage, Protection and Delivery of Therapeutic Proteins. Adv. Healthc. Mater. 12, 2203253 (2023)
  8. Rajan R*, Matsumura K*. Design of self-assembled glycopolymeric zwitterionic micelles as removable protein stabilizing agents. Nanoscale Adv., 5, 1767-1775 (2023)
  9. Kumar N, Oqmhula K, Hongo K, Takagi K, Yusa S, Rajan R, Matsumura K*. Mechanistic insights and importance of hydrophobicity in cationic polymers for cancer therapy. J. Mater. Chem. B, 11, 1456-1468 (2023)
  10. Ishii M, Kamoshita Y, Kurihara Y, Matsumura K, Hyon SH, Ito J, Kashiwazaki N. Successful Production of Offspring Derived from Mouse Zygotes Vitrified with Carboxylated ε-poly-L-lysine and Polyvinyl Alcohol without Serum. J. Reprod. Dev. 69, 53-55 (2023)
  11. Matsumura K*, Rajan R, Ahmed S. Bridging Polymer Chemistry and Cryobiology. Polym. J., 55, 105-115 (2023)

2023 ORIGINAL PAPERS

2022

  1. Hyon W, Hyon SH, Matsumura K.*, Evaluation of the optimal dose for maximizing the anti-adhesion performance of a self-degradable dextran-based material. Carbohydr. Polym. Technol. Appl. 4, 100255 (2022)
  2. Yoshikawa C*, Sakakibara K*, Nonsuwan P, Shobo M, Yuan X, Matsumura K. Cellular Flocculation Driven by Concentrated Polymer Brush Modified Cellulose Nanofibers with Different Surface Charges. Biomacromolecules, 23, 3186-3197 (2022)
  3. Debas A, Matsumura K*, Rajan R*, Polyethylene-glycol-modified Zwitterionic Polymers assisted Protein Aggregation Arrest and Refolding. Mol. Sys. Des. Eng., 7, 1327-1335 (2022)
  4. Jin H, Choi W, Matsumura K, Hyon S-H, Gen Y, Hayashi M, Kawabata T, Ijiri M, Miyoshi K*. Cryopreservation of pig spermatozoa using carboxylated poly-L-lysine as a cryoprotectant. J. Reprod. Dev. 68, 312-317 (2022)
  5. Zhao D, Rajan R, Yusa S, Nakada M, Matsumura K*. Development and structural analysis of dual-thermo-responsive self-assembled zwitterionic micelles. Mater. Adv., 3, 4252-4262 (2022)
  6. Nakaji-Hirabayashi T*, Matsumura K, Ishihara R, Ishiguro T, Nasu H, Kanno M, Ichida S, Hatashima T. Enhanced proliferation and differentiation of human mesenchymal stem cells in the gravity-controlled environment. Artif. Organs, 46, 1760-1770 (2022)
  7. Yuan X, Nonsuwan P, Shobo M, Rajan R, Yamazaki T, Sakakibara K*, Matsumura K*, Yoshikawa C*. Cellular Flocculation Using Concentrated Polymer Brush-Modified Cellulose Nanofibers with Different Fiber Lengths. Biomacromolecules, 23, 1101-1111 (2022)
  8. Le TS, Takahashi M, Isozumi N, Miyazato A, Hiratsuka Y, Matsumura K, Taguchi T, Maenosono S*. Quick and Mild Isolation of Intact Lysosomes Using Magnetic–Plasmonic Hybrid Nanoparticles. ACS Nano, 16, 885-896 (2022)
  9. Rajan R, Kumar N, Matsumura K. Design of an ice recrystallization-inhibiting polyampholyte-containing graft polymer for inhibition of protein aggregation. Biomacromolecules, 23, 487-498 (2022) (Selected as a Journal Inside Front Cover)
  10. Hyon W, Shibata S, Ozaki E, Fujimoto M, Hyon S-H, Matsumura K. Elucidating the degradation mechanism of a self-degradable dextran-based medical adhesive. Carbohydr. Polym., 278, 118949 (2022)
  11. Takada K, Komuro A, Ali MA, Singh M, Okajima M, Matsumura K, Kaneko T. Cell-adhesive gels made of sacran/collagen complexes. Polymer J., 54, 581-589 (2022)
  12. Pitakjakpipop H, Rajan R, Tantisantisom K, Opaprakasit P, Nguyen DD, Ho VA, Matsumura K, Khanchaitit P. Facile Photolithographic Fabrication of Zwitterionic Polymer Microneedle with Protein Aggregation Inhibition for Transdermal Drug Delivery, Biomacromolecules, 23, 365-376 (2022) (Selected as a Journal Inside Front Cover)

2022 ORIGINAL PAPERS

2021

  1. Kumar N, Fazal S, Miyako E, Matsumura K, Rajan R. Avengers against cancer: a new era of nano-biomaterial-based therapeutics, Mater. Today, 51, 317-349 (2021) (Selected as a Journal Front Cover)
  2. Ota A, Hyon S-H, Sumi S, Matsumura K. Gene expression analysis of human induced pluripotent stem cells cryopreserved by vitrification using StemCell Keep. Biochem. Biophys. Rep., 28, 101172 (2021)
  3. 山﨑椋太、Robin Rajan、 林文晶、 長島敏雄、 松村和明　側鎖構造の異なる両性電解質高分子による凍結保護効果。低温生物工学会誌、67, 125-128 (2021)
  4. Küçük N, Raza S, Matsumura K, Uçan U, Serin İ, Ceylan A, Aksoy M. Effect of Different Carboxylated Poly L-lysine and Dimethyl Sulfoxide Combinations on Post Thaw Rabbit Sperm Functionality and Fertility. Cryobiology, 102, 127-132 (2021)
  5. Matsumura K, Rajan R. Oxidized Polysaccharides as Green and Sustainable Biomaterials. Curr. Org. Chem., 25, 1483-1496 (2021)
  6. Fukuda Y, Higashiya M, Obata T, Basaki K, Yano M, Matsumura K, Ono K, Ohba T, Okamoto Y, Nishijima K, Seki S. Small-volume vitrification and rapid warming yield high survivals of one-cell rat embryos in cryotubes. Biol. Reprod., 105, 258-266 (2021)
  7. Matsumura K, Hayashi F, Nagashima T, Rajan R, Hyon S-H. Molecular mechanisms of cell cryopreservation with polyampholytes studied by solid-state NMR. Commun. Mater., 2, 15 (2021)
  8. Rajan R, Ahmed S, Sharma N, Nishant K, Debas A, Matsumura K. Review of the current state of protein aggregation inhibition from a materials chemistry perspective: special focus on polymeric materials. Mater. Adv., 2, 1139-1179 (2021) (Selected as a Journal Back Cover)
  9. Saari RA, Maeno R, Marujiwat W, Nasri MS, Matsumura K, Yamaguchi M. Modification of poly(vinyl alcohol) fibers with lithium bromide. Polymer, 213, 123193 (2021)

2021 ORIGINAL PAPERS

2020

  1. Kawasaki Y, Kohaya N, Shibao Y, Suyama A, Kageyama A, Fujiwara K, Kamoshita M, Matsumura K, Hyon S-H, Ito J, Kashiwazaki N. Carboxylated ε-poly-L-lysine, a cryoprotective agent, is an effective partner of ethylene glycol for the vitrification of embryos at various preimplantation stages. Cryobiology, 97, 245-249 (2020)
  2. 塚田友梨子、松村和明　浸透圧ダメージ保護機能に伴うカルボキシル化ポリリジンの凍結保護効果。低温生物工学会誌、66、111-114 (2020)
  3. Chimpibul W, Nakaji-Hirabayashi T, Yuan X, Matsumura K. Controlling the degradation of cellulose scaffolds with Malaprade oxidation for tissue engineering. J. Mater. Chem. B, 8, 7904-7913 (2020) (Selected as a Journal Inside Front Cover)
  4. Matsumura K, Hatakeyama S, Naka T, Ueda H, Rajan R, Tanaka D, Hyon SH. Molecular design of polyampholytes for vitrification-induced preservation of three-dimensional cell constructs without using liquid nitrogen. Biomacromolecules, 21, 3017-3025 (2020) (Selected as a Journal Front Cover)
  5. Hayashi A, Maehara M, Uchikura A, Matsunari H, Matsumura K, Hyon SH, Sato M, Nagashima H. Development of an efficient vitrification method for chondrocyte sheets for clinical application. Regenerative Therapy, 14, 215-221 (2020)
  6. Rajan R, Pangkom N, Matsumura K. Design of Stimuli-Responsive Polyampholytes and Their Transformation into Micro-Hydrogels for Drug Delivery. ACS Symposium Series, Polymers in Therapeutic Delivery, 47-62 (2020)
  7. 鴨下真紀、中野成実、藤原克祥、須山あゆみ、松村和明、玄丞烋、伊藤潤哉、柏崎直巳　カルボキシル基導入ポリリジンを用いたラット初期胚のガラス化保存法の開発。J. Mamm. Ova. Res., 37, 31-35 (2020)
  8. Ogawa H, Nakaji-Hirabayashi T, Matsumura K, Yoshikawa C, Kitano H, Saruwatari Y. Novel anti-biofouling and drug releasing materials for contact lenses. Colloids Surf. B Biointerfaces 189, 110859 (2020)
  9. Matsumura K. Nanocomposite Hydrogels for Biomedical Applications. Applied Sci. 10, 389 (2020)

2020 ORIGINAL PAPERS

2019

  1. Zhao D, Rajan R, Matsumura K, Dual Thermo- and pH-responsive Behavior of Double Zwitterionic Graft Copolymers for Suppression of Protein Aggregation and Protein Release. ACS Applied Mater. Interf. 11, 39459-39469 (2019)
  2. Ahmed S, Nakaji-Hirabayashi T, Rajan R, Zhao D, Matsumura K, Cytosolic delivery of quantum dots mediated by freezing and hydrophobic polyampholytes in RAW 264.7 cells. J. Mater. Chem. B, 7, 7387-7395 (2019)
  3. Sharma N, Rajan R, Makhaik S, Matsumura K, A comparative study of protein aggregation arrest by zwitterionic polysulfobetaines: Using contrasting raft agents. ACS Omega, 4, 12186-12193 (2019)
  4. Patel M, Nakaji-Hirabayashi T, Matsumura K, Effect of dual-drug–releasing micelle-hydrogel composite on wound healing in vivo in full-thickness excision wound rat model. J. Biomed. Mater. Res. A. 107A, 1094-1106 (2019)
  5. Nonsuwan P, Matsumura K, Amino-Carrageenan @ Polydopamine Microcomposites as Initiators for the Degradation of Hydrogel by Near Infrared Irradiation for Controlled Drug Release. ACS Appl. Polym. Mater. 1, 286-297 (2019)
  6. Nonsuwan P, Matsugami A, Hayshi F, Hyon S.H, Matsumura K, Controlling the degradation of an oxidized dextran-based hydrogel independent of the mechanical properties. Carbohydr Polym, 204, 131-141 (2019)
  7. Ohara Y, Nakai K, Ahmed S, Matsumura K, Ishihara K, Yusa S.I., pH-Responsive Polyion Complex Vesicle with Polyphosphobetaine Shells. Langmuir, 35, 1249-1256 (2019)
  8. Ahmed S, Matsumura K*, Hamada T*, Hydrophobic polyampholytes and non-freezing cold temperature stimulate internalization of Au nanoparticles to zwitterionic liposomes. Langmuir, 35, 1740-1748 (2019).

2019 ORIGINAL PAPERS

2018

  1. Sornkamnerd S, Okajima M.K, Matsumura K, Kaneko T. Micropatterned Cell Orientation of Cyanobacterial Liquid-Crystalline Hydrogels. ACS Appl. Mater. Interf. 10, 44834-44843 (2018)
  2. Zhao Y, Terai W, Hoshijima Y, Gotoh K, Matsuura K, Matsumura K. Development and Characterization of a Poly (Vinyl Alcohol)/Graphene Oxide Composite Hydrogel as An Artificial Cartilage Material. Applied Sci. 8, 2272 (2018)
  3. Ahmed S, Okuma K, Matsumura K, Comparative analysis of the cellular entry of polystyrene and gold nanoparticles using the freeze concentration method. Biomater Sci, 6, 1791-1799 (2018).
  4. Rajan R, Suzuki Y, Matsumura K, Zwitterionic Polymer Design that Inhibits Aggregation and Facilitates Insulin Refolding: Mechanistic Insights and Importance of Hydrophobicity. Macromol Biosci, 18, 1800016 (2018)
  5. Sornkamnerd S, Okajima MK, Matsumura K, Kaneko T, Surface-Selective Control of Cell Orientation on Cyanobacterial Liquid Crystalline Gels. ACS Omega, 3, 6554-6559 (2018)
  6. Ahmed S, Miyawaki O Matsumura K, Enhanced Adsorption of a Protein–Nanocarrier Complex onto Cell Membranes through a High Freeze Concentration by a Polyampholyte Cryoprotectant. Langmuir, 34, 2352-2362 (2018)

2018 ORIGINAL PAPERS

2017

  1. Rajan R, Matsumura K, Tuneable dual-thermoresponsive core–shell nanogels exhibiting UCST and LCST behavior. Macromol. Rapid Comm., 38, 1700478 (2017)
  2. Takahashi M, Mohan P, Mukai K, Takeda Y, Matsumoto T, Matsumura K, Takakura M, Arai H, Taguchi T, Maenosno S, Magnetic Separation of Autophagosomes from Mammalian Cells using Multifunctional Hybrid Nanobeads. ACS Omega, 2, 4929-4937 (2017)
  3. Ahmed S, Miyawaki O, Matsumura K, Role of cryoprotectants in freeze concentration technology for gene delivery process. Cryoiol Cryotechnol., 63, 147-154 (2017)
  4. Ahmed S, Nakaji-Hirabayashi T, Watanabe T, Hohsaka T, Matsumura K. Freezing Assisted Gene Delivery Combined with Polyampholyte Nanocarriers. ACS Biomater. Sci. Eng., 3, 1677-1689 (2017)
  5. Ahmed S, Fujita S, Matsumura K., A Freeze-Concentration and Polyampholyte-Modified Liposome-Based Antigen Delivery System for Effective Immunotherapy. Adv. Healthc. Mat. 6, 1700207 (2017)
  6. Patel M., Kaneko T., Matsumura K., Switchable release nano-reservoirs for co-delivery of drugs via a facile micelle-hydrogel composite. J. Mater. Chem. B. 5, 3488-3497 (2017) (Selected as a Journal Front Cover)
  7. Sakaguchi T, Nagano S, Hara M, Hyon S.H., Patel M, Matsumura K. Facile preparation of transparent poly(vinyl alcohol) hydrogels with uniform microcrystalline structure by hot pressing without using organic solvents. Polym J. 49, 535-542 (2017)
  8. Kamoshita M, Kato T, Fujiwara K, Namiki T, Matsumura K, Hyon SH, Ito J, Kashiwazaki N., Vitrification with carboxylated ε-poly-L-lysine improves the in vitro and in vivo developmental ability of vitrified pronuclear-stage pig embryos. Plos One, 12, e0176711 (2017)
  9. Rajan R, Matsumura K. Inhibition of protein aggregation by zwitterionic polymer-based core-shell nanogels. Sci. Rep., 7, 45777; doi: 10.1038/srep45777 (2017)
  10. Das E, Matsumura K. Tunable phase‐separation behavior of thermoresponsive polyampholytes through molecular design. J. Polym. Sci. A. Polym. Chem. 55, 876-884 (2017)
  11. Tsuji Y, Iwasaki T, Ogata H, Matsumoto Y, Kokeguchi S, Matsumura K, Hyon S-H, Shiotani M. The beneficial effect of carboxylated poly-L-lysine on cryosurvival of vitrified early stage embryos. Cryoletters, 38, 1-6 (2017)
  12. Ota A, Matsumura K, Lee JJ, Sumi S, Hyon SH. StemCell KeepTM is effective for cryopreservation of human embryonic stem cells by vitrification. Cell Transplant, 26, 773-787 (2017)

2017 ORIGINAL PAPERS

2016

  1. Jain M, Matsumura K, Thixotropic injectable hydrogel using a polyampholyte and nanosilicate prepared directly after cryopreservation. Mater. Sci. Eng. C., 69, 1273-1281 (2016)
  2. Dureamae I, Nishida M, Nakaji-Hirabayashi T, Matsumura K, Kitano H. Biodegradable shape memory polymers functionalized with anti-biofouling interpenetrating polymer networks. J Mater Chem B 4, 5394-5404 (2016)
  3. Ahmed S, Fujita S, Matsumura K. Enhanced Protein Internalization and Efficient Endosomal Escape Using Polyampholyte-Modified Liposomes and Freeze Concentration. Nanoscale 8, 15888-15901 (2016) (Selected as a Journal Back Cover)
  4. Ahmed S, Matsumura K. Novel Concentration-Based Freezing Method for Efficient Protein Delivery. Cryobiol. Cryotechnol. 62, 143-147 (2016)
  5. Matsumura K, Kawamoto K, Takeuchi M, Yoshimura S, Tanaka D, Hyon SH. Cryopreservation of a Two-Dimensional Monolayer Using a Slow Vitrification Method with Polyampholyte to Inhibit Ice Crystal Formation. ACS Biomater Sci Eng, 2, 1023-1029, (2016)
  6. Chimpibul W, Nagashima T, Hayashi F, Nakajima N, Hyon SH, Matsumura K. Dextran Oxidized by a Malaprade Reaction Shows Main Chain Scission Through a Maillard Reaction Triggered by Schiff Base Formation Between Aldehydes and Amines. J Polym Sci Part A. Polym Chem, 54, 2254-2260, (2016).
  7. Rajan R, Hayashi F, Nagashima T, Matsumura K, Toward a Molecular Understanding of the Mechanism of Cryopreservation by Polyampholytes: Cell Membrane Interactions and Hydrophobicity. Biomacromolecules, 17, 1882-1893, (2016)
  8. Jain M, Matsumura K, Polyampholyte- and nanosilicate-based soft bionanocomposites with tailorable mechanical and cell adhesion properties. J Biomed Mater Res A, 104A, 1379-1386, (2016).

2016 ORIGINAL PAPERS

2015

  1. Uemura M, Ishiguro H, Matsumura K. Effect of Carboxylated Poly-L-lysine on Morphological Change of Adherent Neuron-like Cells after Extracellular-freezing and Thawing. Cryobiol Cryotechnol, 61, 125-129, (2015)
  2. Rajan R, Matsumura K. A zwitterionic polymer as a novel inhibitor of protein aggregation. J Mater Chem B, 3, 5683-5689, (2015) (Selected as a Journal Cover)
  3. Takahashi M, Mohan P, Nakade A, Higashimine K, Mott D, Hamada T, Matsumura K, Taguchi T, Maenosono S. Ag/FeCo/Ag Core/Shell/Shell Magnetic Nanoparticles with Plasmonic Imaging Capability. Langmuir, 31，2228-2236, (2015).

2015 ORIGINAL PAPERS

2014年以前の業績はこちらからご覧ください。 ≫

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